Lupus Warning Signs: How to Recognize and Manage This Elusive Autoimmune Disease

6. Unexplained Fevers
Low-grade fevers (99--101°F) without an obvious cause are another common lupus symptom. These fevers, caused by immune system inflammation, can leave you feeling weak and unwell. While not high enough to cause alarm on their own, their persistence is a red flag.
When to act: If you frequently run a mild fever without signs of infection, and it lasts for days or keeps returning, lupus-related inflammation could be to blame.