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Which antibiotic is known for having the best cerebrospinal fluid penetration in cases of bacterial meningitis?
Correct Incorrect Ceftriaxone penetrates the bloodbrain barrier effectively and is first-line for bacterial meningitis. Vancomycin may be used adjunctively but has variable CSF levels. Gentamicin poorly penetrates CSF. Amoxicillin is not adequate for most meningitis pathogens.